CNS & Neurological Disorders - Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular targets involved in neurological and central nervous system (CNS) disorders e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal will contain a series of timely in-depth reviews written by leaders in the field covering a range of current topics on drug targets involved in neurological and CNS disorders. As the discovery, identification, characterization and validation of novel human drug targets for neurological and CNS drug discovery continues to grow; this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.

CNS & Neurological Disorders - Drug Targets (Formerly Current Drug Targets - CNS & Neurological Disorders) was previously published as Current Drug Targets-CNS & Neurological Disorders.

Publisher: Bentham Science Publishers

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Volume 11, Number 8, December 2012

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Articles

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Free Content Commentary (Research Highlights: Utilizing Neuro-Inflammation: Turning Degeneration to Regeneration)
pp. 953-954(2)
Authors: Cui, Ying; Li, Jiang; Arias-Carrion, Oscar; Yuan, Ti-Fei

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C. elegans as a Genetic Model System to Identify Parkinson's Disease- Associated Therapeutic Targets
pp. 957-964(8)
Authors: Vistbakka, Julia; VanDuyn, Natalia; Wong, Garry; Nass, Richard

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Open Access Effects of α-Synuclein Overexpression in Transgenic Caenorhabditis elegans Strains
pp. 965-975(11)
Authors: Bodhicharla, Rakesh; Nagarajan, Archana; Winter, Jody; Adenle, Ademola; Nazir, Aamir; Brady, Declan; Vere, Kelly; Richens, Jo; O'Shea, Paul; R. Bell, David; de Pomerai, David

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Iridoid Compound 10-O-trans-p-Coumaroylcatalpol Extends Longevity and Reduces Alpha Synuclein Aggregation in Caenorhabditis elegans
pp. 984-992(9)
Authors: Shukla, Virendra; C. Phulara, Suresh; Yadav, Deepti; Tiwari, Sudeep; Kaur, Supinder; M. Gupta, M.; Nazir, Aamir; Pandey, Rakesh

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An Overview on Potential Neuroprotective Compounds for Management of Alzheimer's Disease
pp. 1006-1011(6)
Authors: Ahmed Sheikh, Ishfaq; Ali, Riyasat; A. Dar, Tanveer; Amjad Kamal, Mohammad

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Nuclear Factor Erythroid 2 - Related Factor 2 Signaling in Parkinson Disease: A Promising Multi Therapeutic Target Against Oxidative Stress, Neuroinflammation and Cell Death
pp. 1015-1029(15)
Authors: Kumar, Hemant; Koppula, Sushruta; Kim, In-Su; Vasant More, Sandeep; Kim, Byung-Wook; Choi, Dong-Kug

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The Protective Effects of Jatrorrhizine on β-Amyloid (25-35)-Induced Neurotoxicity in Rat Cortical Neurons
pp. 1030-1037(8)
Authors: Luo, Tao; Jiang, Wei; Kong, Yan; Li, Sheng; He, Feng; Xu, Jie; Wang, Hua-Qiao

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Geniposide Regulates Insulin-Degrading Enzyme Expression to Inhibit the Cytotoxicity of Aβ1-42 in Cortical Neurons
pp. 1045-1051(7)
Authors: Yin, Fei; Zhang, Yonglan; Guo, Lixia; Kong, Shuzhen; Liu, Jianhui

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Acetylcholinesterase Inhibitors as Pretreatment Before Acute Exposure to Organophosphates: Assessment Using Methyl-Paraoxon
pp. 1052-1060(9)
Authors: E. Lorke, Dietrich; Y. Hasan, Mohamed; M. Nurulain, Syed; Shafiullah, Mohamed; Kuca, Kamil; A. Petroianu, Georg

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Restless Legs Syndrome in Multiple Sclerosis
pp. 1061-1069(9)
Authors: Zecca, Chiara; Manconi, Mauro; Fulda, Stephany; Gobbi, Claudio

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Outcome-Dependent Global Similarity Analysis of Imbalanced Core Signaling Pathways in Ischemic Mouse Hippocampus
pp. 1070-1082(13)
Authors: Liu, Jun; Zhang, Zhan-jun; Zhou, Cai-xiu; Wang, Yi; Cheng, Yi-yu; Darrel Duan, Da-yue; Wang, Yong-yan; Wang, Zhong

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