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CNS & Neurological Disorders - Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular targets involved in neurological and central nervous system (CNS) disorders e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal will contain a series of timely in-depth reviews written by leaders in the field covering a range of current topics on drug targets involved in neurological and CNS disorders. As the discovery, identification, characterization and validation of novel human drug targets for neurological and CNS drug discovery continues to grow; this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.

CNS & Neurological Disorders - Drug Targets (Formerly Current Drug Targets - CNS & Neurological Disorders) was previously published as Current Drug Targets-CNS & Neurological Disorders.

Publisher: Bentham Science Publishers

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Volume 11, Number 4, June 2012

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Articles

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Overview of Tyrosine Hydroxylase in Parkinson's Disease
pp. 350-358(9)
Authors: Zhu, Yanzhen; Zhang, Jing; Zeng, Yanjun

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Paradoxical Sleep Deprivation Modulates Tyrosine Hydroxylase Expression in the Nigrostriatal Pathway and Attenuates Motor Deficits Induced by Dopaminergic Depletion
pp. 359-368(10)
Authors: M.S. Lima, Marcelo; L. Andersen, Monica; B. Reksidler, Angela; C. Ferraz, Anete; A.B.F. Vital, Maria; Tufik, Sergio

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Targeting Parkinson's - Tyrosine Hydroxylase and Oxidative Stress as Points of Interventions
pp. 369-380(12)
Authors: Shahnawaz Khan, Mohd; Tabrez, Shams; Priyadarshini, Medha; Priyamvada, Shubha; M. Khan, Mohd

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The Function of Tyrosine Hydroxylase in the Normal and Parkinsonian Brain
pp. 381-386(6)
Authors: Tolleson, Christopher; Claassen, Daniel

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RNAi of cat-2, a Putative Tyrosine Hydroxylase, Increases Alpha Synuclein Aggregation and Associated Effects in Transgenic C. elegans
pp. 387-394(8)
Authors: Kaur, Supinder; Raj Sammi, Shreesh; Jadiya, Pooja; Nazir, Aamir

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A Synopsis on the Role of Tyrosine Hydroxylase in Parkinson's Disease
pp. 395-409(15)
Authors: Tabrez, Shams; R. Jabir, Nasimudeen; Shakil, Shazi; H. Greig, Nigel; Alam, Qamre; M. Abuzenadah, Adel; A. Damanhouri, Ghazi; A. Kamal, Mohammad

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New Agents Promote Neuroprotection in Parkinson's Disease Models
pp. 410-418(9)
Author: Maria Miranda Santos, Claudia

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Redox Sensitivity of Tyrosine Hydroxylase Activity and Expression in Dopaminergic Dysfunction
pp. 419-429(11)
Authors: Di Giovanni, Giuseppe; Pessia, Mauro; Di Maio, Roberto

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Mitochondria as an Easy Target to Oxidative Stress Events in Parkinson's Disease
pp. 430-438(9)
Authors: Reale, Marcella; Pesce, Mirko; Priyadarshini, Medha; A Kamal, Mohammad; Patruno, Antonia

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Motor and Non-Motor Features of Parkinson's Disease – A Review of Clinical and Experimental Studies
pp. 439-449(11)
Authors: M.S. Lima, Marcelo; F. Martins, Emerson; Marcia Delattre, Ana; B. Proenca, Mariana; A. Mori, Marco; Carabelli, Bruno; C. Ferraz, Anete

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A Brief Overview of Tyrosine Hydroxylase and α-Synuclein in the Parkinsonian Brain
pp. 456-462(7)
Authors: Khan, Wajihullah; Priyadarshini, Medha; A. Zakai, Haytham; A. Kamal, Mohammad; Alam, Qamre

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Molecular Docking Study of Catecholamines and [4-(Propan-2-yl) Phenyl]Carbamic acid with Tyrosine Hydroxylase
pp. 463-468(6)
Authors: Parveen, Zahida; Sulaman Nawaz, Muhammad; Shakil, Shazi; H. Greig, Nigel; A. Kamal, Mohammad

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Tyrosine Hydroxylase Gene: Another Piece of the Genetic Puzzle of Parkinson's Disease
pp. 469-481(13)
Authors: Bademci, Guney; M. Vance, Jeffery; Wang, Liyong

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Alzheimer's Disease And Type 2 Diabetes: Exploring The Association To Obesity And Tyrosine Hydroxylase
pp. 482-489(8)
Authors: Priyadarshini, Medha; A. Kamal, Mohammad; H. Greig, Nigel; Realef, Marcella; M. Abuzenadah, Adel; G.A. Chaudhary, Adeel; A. Damanhouri, Ghazi

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