Home >> CNS & Neurological Disorders - Drug Targets (Formerly Current Drug Targets, Volume 7, Number 1
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CNS & Neurological Disorders - Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular targets involved in neurological and central nervous system (CNS) disorders e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal will contain a series of timely in-depth reviews written by leaders in the field covering a range of current topics on drug targets involved in neurological and CNS disorders. As the discovery, identification, characterization and validation of novel human drug targets for neurological and CNS drug discovery continues to grow; this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.

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Publisher: Bentham Science Publishers

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Volume 7, Number 1, February 2008

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Articles

Editorial [ Neurodegenerative Disorders: From Molecules to Man (Part 2) Guest Editors: Giuseppe Di Giovanni, Vincenzo Di Matteo and Ennio Esposito ]
pp. 1-2(2)
Authors: Matteo, Vincenzo D.; Esposito, Ennio; Giovanni, Giuseppe D.i.

Alzheimer Disease and the Role of Free Radicals in the Pathogenesis of the Disease
pp. 3-10(8)
Authors: Perry, George; Moreira, Paula I.; Santos, Maria S.; Oliveira, Catarina R.; Shenk, Justin C.; Nunomura, Akihiko; Smith, Mark A.; Zhu, Xiongwei

Molecular Insights and Therapeutic Targets in Amyotrophic Lateral Sclerosis
pp. 11-19(9)
Authors: Al-Chalabi, Ammar; Tripathi, Vineeta B.

Is the Deficiency of Vitamin B12 Related to Oxidative Stress and Neurotoxicity in Parkinson's Patients?
pp. 20-27(8)
Authors: Qureshi, G. A.; Qureshi, Aftab A.; Devrajani, Bika R.a.m.; Chippa, M. A.; Syed, S. A.l.i.

Will it Ever Become Possible to Prevent Dopaminergic Neuronal Degeneration?
pp. 28-44(17)
Author: Giovanni, Giuseppe D.

Editorial [ Targeting Neurotrophic Factors, Their Receptors, and Signalling Pathways with Small Molecule Mimetics and Modulators to Achieve Neuroprotection and Regeneration Guest Editor: Stephen D. Skaper ]
pp. 45-45(1)
Author: Skaper, Stephen D.

The Biology of Neurotrophins, Signalling Pathways, and Functional Peptide Mimetics of Neurotrophins and their Receptors
pp. 46-62(17)
Author: Skaper, Stephen D.

Small Molecule Modulation of p75 Neurotrophin Receptor Functions
pp. 63-70(8)
Authors: Longo, Frank M.; Massa, Stephen M.

Targeting Neurotrophin Receptors in the Central Nervous System
pp. 71-82(12)
Authors: Mocchetti, Italo; Brown, Milton

MAP Kinase Pathways in Neuronal Cell Death
pp. 83-97(15)
Authors: Philpott, Karen L.; Facci, Laura

Stem Cells for the Treatment of Neurological Disorders
pp. 98-109(12)
Authors: Rao, Mahendra S.; Khanna, Aparna; Shin, Soojung

Tandem Repeat Peptide Strategy for the Design of Neurotrophic Factor Mimetics
pp. 110-119(10)
Authors: Williams, Gareth; Molina-Holgado, Francisco; Doherty, Patrick

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