Current Understanding of Dietary Polyphenols and their Role in Health and Disease

Authors: Pandey, Kanti B.; Rizvi, Syed I.b.r.a.h.i.m.

Source: Current Nutrition & Food Science, Volume 5, Number 4, November 2009 , pp. 249-263(15)

Publisher: Bentham Science Publishers

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Abstract:

Polyphenols are among a wide variety of active photochemicals present in the human diet. Basic researches and epidemiological studies have shown the inverse association between risk of cancer, CVDs, diabetes, several age related chronic diseases and intake of diet rich in polyphenols. Recent researches have opened the possibility of dietary polyphenols to be considered as phytomedicine. Most of the studies on the bioactivity of polyphenols have been conducted on animal models and in in vitro systems, direct studies on humans are few and results inconclusive. The bioavailability and biotransformation of polyphenols in humans needs to be studied. The present review provides an update about dietary polyphenols covering their nature, occurrence, bioavailability, and possible health benefits in relation to human diseases.

Keywords: Polyphenols; occurrence; classification; bioavailability; human diseases; bioactivity

Document Type: Research article

DOI: http://dx.doi.org/10.2174/157340109790218058

Publication date: 2009-11-01

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Current Nutrition & Food Science publishes frontier reviews on all the latest advances on basic and clinical nutrition and food sciences. The journal's aim is to publish the highest quality review articles dedicated to research in the field. The journal is essential reading for all nutrition and food scientists.