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Preparation of Ni-cysteine Hollow Spheres with Ferromagnetic Property and Good Biocompatibility

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In this work, magnetic Ni-cysteine hollow spheres were firstly fabricated by a facile room temperature self-assembly method. The most outstanding advantage of these hollow spheres is that the biocompatibility of amino acid and the magnetic property of metal nickel ions are successfully combined. Their coercivity in the magnetic measurement is 90 Oe at 80 K. This ferromagnetic performance and the satisfying blood compatibility in the anticoagulation test make them show promising applications in biological technique, especially the targeted drug delivery.

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Keywords: APTT; EDS; FC; FT-IR; Hollow spheres; IR spectra; MRI; Ni(NO3)2; Ni-cysteine; PT; Raman spectrum; TEM; TT; ZFC; amino acid; anticoagulation; biocompatibility; carboxylate groups; centrifugation; cysteine; drug delivery; ferromagnetic; metal-amino acid; nanospheres; paramagnetic; self-assembly; spheres; transition metal

Document Type: Research Article

Publication date: 01 December 2010

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  • Current Nanoscience publishes authoritative reviews and original research reports, written by experts in the field on all the most recent advances in nanoscience and nanotechnology. All aspects of the field are represented including nano- structures, synthesis, properties, assembly and devices. Applications of nanoscience in biotechnology, medicine, pharmaceuticals, physics, material science and electronics are also covered. The journal is essential to all involved in nanoscience and its applied areas.
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