Skip to main content

Properties of Hydroxyapatite - Hyaluronic Acid Nano-Composite Sol and its Interaction with Natural Bones and Collagen Fibers

Buy Article:

$63.00 plus tax (Refund Policy)

Biocompatible nano-composite sol (NCS) comprising nano-crystalline hydroxyapatite (HAp, Ca 10(PO4)6(OH)2) and hyaluronic acid (HYA) was prepared. By varying the relative content of HAp in NCS, strongest network structure was obtained at 10wt% HAp in NCS, as confirmed from a number of circumstance evidences obtained by rheological, thermoanalytical, crystallographical measurements as well as FT-IR spectra. Interaction of NCS with natural bones and gut strings made from gut collagen was then examined in vitro. Adhesion of the collagen fibers with NCS was observed at the fracture surface of natural bones. Gut collagen was disentangled to the fragments of about 10 nm thick, where no NCS was observed, thus, confirming the fact that the adhesive strength between NCS and bone surface is stronger than that among collagen fibers.

No References
No Citations
No Supplementary Data
No Data/Media
No Metrics

Keywords: Adhesive strength; Biocompatible nano-composite sol; Collagen fibers; Hyaluronic acid; Hydroxyapatite

Document Type: Research Article

Affiliations: Department of AppliedChemistry; Faculty of Science and Technology; Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Kanagawa Prefecture, Japan.

Publication date: 2006-08-01

More about this publication?
  • Current Nanoscience publishes authoritative reviews and original research reports, written by experts in the field on all the most recent advances in nanoscience and nanotechnology. All aspects of the field are represented including nano- structures, synthesis, properties, assembly and devices. Applications of nanoscience in biotechnology, medicine, pharmaceuticals, physics, material science and electronics are also covered. The journal is essential to all involved in nanoscience and its applied areas.
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more