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Emerging Role of Colloidal Drug Delivery Systems (CDDS) in NSAID Topical Administration

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NSAIDs are the most commonly prescribed category of drugs for the treatment of musculoskeletal pain and inflammation associated with many conditions. Topical administration of these drugs is always the best choice since adverse effects occur commonly with systemic NSAID therapy.

Colloidal drug delivery systems (CDDS) are interesting systems, which are able to improve the duration of drug residence in the skin and to allow an achievable drug sustained and controlled release compared to conventional topical formulations.

This review focuses on micro and nanoemulsions, vesicular carriers and nanoparticles as novel high efficiency delivery systems of NSAIDs in topical applications.
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Keywords: Dermal; NSAIDs; in vitro; in vivo; nanotechnology; transdermal

Document Type: Research Article

Publication date: 2013-05-01

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  • Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.
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