@article {Iannazzo:2013:0929-8673:1333,
title = "Recent Advances in Carbon Nanotubes as Delivery Systems for Anticancer Drugs",
journal = "Current Medicinal Chemistry",
parent_itemid = "infobike://ben/cmc",
publishercode ="ben",
year = "2013",
volume = "20",
number = "11",
publication date ="2013-04-01T00:00:00",
pages = "1333-1354",
itemtype = "ARTICLE",
issn = "0929-8673",
url = "https://www.ingentaconnect.com/content/ben/cmc/2013/00000020/00000011/art00001",
keyword = "drug delivery systems, Carbon nanotubes, anticancer drugs",
author = "Iannazzo, Daniela and Piperno, Anna and Pistone, Alessandro and Grassi, Giovanni and Galvagno, Signorino",
abstract = "Problems associated with the administration of anticancer drugs, such as limited solubility, poor biodistribution, lack of selectivity, and healthy tissue damage, can be overcome by the implementation of drug delivery systems. A wide range of materials, including liposomes, microspheres,
polymers and recently, carbon nanotubes (CNTs), have been investigated for delivering anticancer drugs on the purpose of reducing the number of necessary administrations, providing more localized and better use of the active agents, and increasing patient compliance. Carbon nanotubes (CNTs)
have attracted particular attention as carriers of biologically relevant molecules due to their unique physical, chemical and physiological properties. The exact relationship between the physical-chemical properties of carbon nanotubes, their cellto- cell interactions, reactivity, and biological/systemic
consequences are relevant issues and it is important to know such inter-relationships beforehand to employ the benefits of these nanomaterials without the hazardous consequences. The purpose of this review is to present highlight of recent developments in the application of carbon nanotubes
as cargoes for anticancer drugs and in the diagnosis of cancer diseases.",
}