Skip to main content

Recent Lipase-Catalyzed Hydrolytic Approaches to Pharmacologically Important β-and γ-Amino Acids

Buy Article:

$55.00 plus tax (Refund Policy)

Kinetic and sequential kinetic enzymatic routes for the synthesis of enantiomeric β- and γ-amino acids through enzymatic ring cleavage of the corresponding lactams in organic solvents or solvent-free systems or a supercritical CO2 medium, and for the enantioselective hydrolysis of the corresponding amino esters in organic solvents are reviewed. In the frame of a practical guide, a simple and rapid GC enantioseparation technique for amino acids, including exact descriptions of selected enzymatic reactions, is additionally presented.
No References
No Citations
No Supplementary Data
No Data/Media
No Metrics

Keywords: GC enantioseparation; burkholderia cepacia lipase PS; candida antarctica lipase B; enantiomer; enzymatic catalysis; kinetic resolution; lipase; organic solvent; sequential resolution; solvent-free system; supercritical CO2; β-amino acid; β-amino ester; β-lactam; γ-amino acid; γ-lactam

Document Type: Research Article

Publication date: 2012-12-01

More about this publication?
  • Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more