Synthesis of Biologically Active Bridged Diazabicycloheptanes
Abstract:The chemistry underlying how diazabicycloheptanes are assembled is described, subdivided according to chemical structure of two types, the 3,6 diazabicyclo[3.1.1]heptane and the 2,5-diazabicyclo[2.2.1]heptane ring system. Detailed information on myriad of activities of compounds derived from the two scaffolds are reported.
Keywords: 2; 3; 5-diazabicyclo[2.2.1]heptanes; 6-diazabicyclo[3.1.1]heptanes; analgesic activity; antibacterial activity; antiinflammatory activity; antipsychotic activity; antitumor activity; ischemic injuries; obesity; synthesis
Document Type: Research Article
Publication date: November 1, 2012
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