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Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.

Publisher: Bentham Science Publishers

Volume 19, Number 23, August 2012

Articles

Free Content EDITORIAL (Hot Topic: Cancer Chemoresistance and DNA Repair)
pp. 3857-3857(1)
Author: Mocellin, Simone

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Synthetic Lethality to Overcome Cancer Drug Resistance
pp. 3858-3873(16)
Authors: Porcelli, L.; E. Quatrale, A.; Mantuano, P.; Silvestris, N.; E. Brunetti, A.; Calvert, H.; Paradiso, A.; Azzariti, A.

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DNA Repair and Resistance to Topoisomerase I Inhibitors: Mechanisms, Biomarkers and Therapeutic Targets
pp. 3874-3885(12)
Authors: Alagoz, M.; C. Gilbert, D.; El-Khamisy, S.; J. Chalmers, A.

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Strategies to Improve the Killing of Tumors Using Temozolomide: Targeting the DNA Repair Protein MGMT
pp. 3886-3892(7)
Authors: Jiang, G.; -T. Li, L.; Xin, Y.; Zhang, L.; -Q. Liu, Y.; -N. Zheng, J.

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Circumventing Melanoma Chemoresistance by Targeting DNA Repair
pp. 3893-3899(7)
Authors: Mocellin, S.; Bertazza, L; Benna, C.; Pilati, P.

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Cancer Resistance to Type II Topoisomerase Inhibitors
pp. 3900-3906(7)
Authors: Pilati, P.; Nitti, D.; Mocellin, S.

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Role of PARP Inhibitors in Cancer Biology and Therapy
pp. 3907-3921(15)
Authors: Davar, D.; H. Beumer, J.; Hamieh, L.; Tawbi, H.

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Polo-Like Kinases Inhibitors
pp. 3937-3948(12)
Authors: Garuti, L.; Roberti, M.; Bottegoni, G.

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Coinage Metal Complexes Against Breast Cancer
pp. 3949-3956(8)
Authors: Biersack, B.; Ahmad, A.; H. Sarkar, F.; Schobert, R.

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Palladacycles as Antimicrobial Agents
pp. 3967-3981(15)
Authors: -S.S.H. Elgazwy, A.; S.M. Ismail, N.; R. Atta-Allah, S.; T. Sarg, M.; H.S. Soliman, D.; Y. Zaki, M.; A. Elgamas, M.

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Glutathione-Related Factors and Oxidative Stress in Autism, A Review
pp. 4000-4005(6)
Authors: Ghanizadeh, A.; Akhondzadeh, S.; Hormozi, M.; Makarem, A.; Abotorabi-Zarchi, M.; Firoozabadi, A.

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Anti-Inflammatory Effect of 3,4-DHPEA-EDA [2-(3,4 -Hydroxyphenyl) ethyl (3S, 4E)- 4-Formyl-3-(2-Oxoethyl)Hex-4-Enoate] on Primary Human Vascular Endothelial Cells
pp. 4006-4013(8)
Authors: Sindona, G.; Caruso, A.; Cozza, A.; Fiorentini, S.; Lorusso, B.; Marini, E.; Nardi, M.; Procopio, A.; Zicari, S.

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AG490 Promotes HIF-1α Accumulation by Inhibiting Its Hydroxylation
pp. 4014-4023(10)
Authors: Fernandez-Sanchez, R.; Berzal, S.; Sanchez-Nino, Maria-Dolores; Neria, F.; Goncalves, S.; Calabia, O.; Tejedor, A.; J. Calzada, M.; Caramelo, C.; J.P. Deudero, J.; Ortiz, A.

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Insight into the Structural Determinants of Imidazole Scaffold-Based Derivatives as P38 MAP Kinase Inhibitors by Computational Explorations
pp. 4024-4037(14)
Authors: Huang, C.; Li, Y.; Ren, H.; Wang, J.; Shao, L.; Zhang, S.; Li, G.; Yang, L.

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