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Some Recent Approaches of Biologically Active Substituted Pyridazine and Phthalazine Drugs

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Abstract:

Nitrogen atom containing heterocyclic compounds, pyridazines, pyridazinones and phthalazines are important structural feature of many biologically active compounds and show diverse pharmacological properties. Pyridazines and phthalazines hold considerable interest relative to the preparation of organic intermediates and physiologically active compounds. On the basis of literature, pyridazines, pyridazinone and phthalazines further focus our attention because of their easy fictionalization at various ring positions, which makes them attractive synthetic compounds for designing and development of the novel pyridazines and phthalazines drugs in future.

Keywords: Biological activities; designing; development; drugs; heterocyclic; organic compounds; phthalazines; pyridazines; pyridazinone; structural feature

Document Type: Research Article

DOI: http://dx.doi.org/10.2174/092986712800672139

Affiliations: Guru Ram Das (Post Graduate) Institute of Management and Technology, 214- Rajpur Road, Dehradun, 248009 (UK), India.

Publication date: June 1, 2012

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  • Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.
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