Discovery of Selective Small Molecular TACE Inhibitors for the Treatment of Rheumatoid Arthritis
Keywords: Rheumatoid arthritis; design; inflammatory disease; matrix metalloproteinases; pharmacokinetic; selective inhibitors; structure-activity relationship; synthesis; tumour necrosis factor-α converting enzyme; zinc binding group
Document Type: Research Article
Affiliations: Jiangsu Key Laboratory for High Technology Research of TCM Formulae, Nanjing University of Chinese Medicine, 138 Xianlin Road, 210046, Nanjing, Jiangsu, P.R. China.
Publication date: 2012-06-01
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