CuAAC Click Chemistry Accelerates the Discovery of Novel Chemical Scaffolds as Promising Protein Tyrosine Phosphatases Inhibitors
Keywords: CuAAC; Protein tyrosine phosphatase; amino acid; bidentate; carbohydrate; click chemistry; competitive inhibitor; dephosphorylation; drug discovery; in situ screening; isoxazole acid; ketocarboxylic acid; salicylic acid; tyrosine phosphorylation
Document Type: Research Article
Affiliations: Key Laboratory for Advanced Materials & Institute of Fine Chemicals, East China University of Science and Technology, Shanghai 200237, P.R. China.
Publication date: 2012-05-01
- Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.