2-Hydroxy-1-oxo-1,2-dihydroisoquinoline-3-carboxylic Acid with Inbuilt β-NHydroxy-γ-keto-acid Pharmacophore as HCV NS5B Polymerase Inhibitors
Keywords: Hepatitis C virus; active site inhibitors; lead compound; metal chelation; non-structural protein 5B (NS5B) polymerase; pharmacophore; pyrophosphate mimic; structure-activity relationship; α,γ-diketo acid; β-N-Hydroxy-γ-keto-acid
Document Type: Research Article
Publication date: 2012-02-01
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