Protective and Therapeutic Effects of Ghrelin in the Gut

Authors: Warzecha, Z.; Dembinski, A.

Source: Current Medicinal Chemistry, Volume 19, Number 1, January 2012 , pp. 118-125(8)

Publisher: Bentham Science Publishers

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Abstract:

Ghrelin, a peptide predominantly produced in the stomach exhibits numerous physiological functions, including stimulation of growth hormone release, food intake and gastric empting, and regulation of energy expenditure. This peptide exhibits also some protective and healing-promoting effects. This review summarizes the recent findings concerning animal and human data showing protective and therapeutic effects of ghrelin in the gut.

Keywords: Colitis; food intake; gastric ulcer; ghrelin; healing; pancreatitis; protection; physiological functions; hormone; therapeutic effects

Document Type: Research article

DOI: http://dx.doi.org/10.2174/092986712803414051

Publication date: 2012-01-01

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Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.