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Defensins and Other Biocidal Proteins from Bean Seeds with Medicinal Activities

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It is well known that legumes, especially soybeans, are beneficial to health due to the presence of saponins and an abundance of fiber and proteins. Defensins and other related defense proteins with antifungal activity in legumes act against fungi which are human pathogens and also against phytopathogenic fungi. These proteins exhibit HIV-1 reverse transcriptase inhibitory and antitumor activities. Some of these proteins have remarkable stability to proteases, and changes in pH and temperature and are promising therapeutic candidates.

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Keywords: Defensins; HIV-1 reverse transcriptase inhibitory activity; antifungal; antitumor activities; antitumor activity; bean seeds; beans; biocidal proteins; medicinal activity; phytopathogenic fungi

Document Type: Research Article

Publication date: 01 December 2011

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  • Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.
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