Alkaloids and Flavonoids as α1-Adrenergic Receptor Antagonists
Since the subtypes of α1-adrenergic receptor have been thoroughly determined, to date medicinal chemists raise their deliberation on how to conceive selective α1-adrenergic receptor antagonist with the minimal side effects. It needs to be well recognized that natural products can exist as a significant source of drug leads, thus portraying a consequential capacity in drug design and development. The current review article would like to present a comprehensive survey on natural products, mainly including alkaloids and flavonoids, which exhibit α1-adrenergic receptor antagonistic activities.
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Document Type: Research Article
Publication date: 01 November 2011
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