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Chromenopyridines: Promising Scaffolds for Medicinal and Biological Chemistry

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Abstract:

Chromenopyridines constitute a structurally diverse class of compounds with a wide range of bioactivities and increasing presence in drugs. Here we analyze the scope of the synthetic methodology to access this nucleus with emphasis on multicomponent reactions and robust methodologies. Reactivity issues, medicinal applications and other properties are also reviewed.





Keywords: Azines; benzopyran; chromene; coumarin; drug-like scaffolds; heterocycles; multicomponent reactions; privileged structures; pyridine; synthetic methods

Document Type: Research Article

DOI: https://doi.org/10.2174/092986711797535272

Publication date: 2011-11-01

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  • Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.
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