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How Would Composite Traditional Chinese Medicine Protect the Brain - An Example of the Composite Formula “Pien Tze Huang”

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Chinese medicine has a long history of several thousand years. The main form of Traditional Chinese Medicine (TCM) is composite, i.e. a mixture of up to 10 medicinal products. Thus a composite prescription of 4-5 kinds of Chinese medicinal products may contain several hundred kinds of chemical composition. The active ingredients and clinical efficacy of which are difficult to characterize. We aim to review the Chinese literature of TCMs with neuroprotective effects. We illustrate with our study on Pien Tze Huang (PZH) the use of in vivo tests in the study of composite TCM. Our results show evidence that PZH might have neuropreventive effects in rats.

Keywords: Angong Niuhuang Wan; Cerebral ischemia; Compound Danshen Dripping Pill; Ginkgo Biloba; Pien Tze Huang; cerebral stroke; composite traditional Chinese Medicine; functional magnetic resonance imaging; neuroprotection; water maze

Document Type: Research Article


Publication date: August 1, 2011

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  • Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.

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