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Nitric Oxide and Cyclic GMP Signaling Pathway as a Focus for Drug Development

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Recent progress in understanding of the nitric oxide and cGMP signaling pathway provided evidence for mechanism of action of known drugs and identified novel targets for drug development. These discoveries resulted in numerous efforts in drug and formulation discovery. Some of the most promising approaches were applied for efficient therapies of various diseases.

Keywords: Nitric oxide; cGMP; drug and formulation discovery; drug development; guanylyl cyclase; nitric oxide synthase; numerous efforts; phosphodiesterase; promising approaches; traditional Chinese medicine

Document Type: Research Article


Publication date: August 1, 2011

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  • Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.

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