Nitric Oxide and Cyclic GMP Signaling Pathway as a Focus for Drug Development
Abstract:Recent progress in understanding of the nitric oxide and cGMP signaling pathway provided evidence for mechanism of action of known drugs and identified novel targets for drug development. These discoveries resulted in numerous efforts in drug and formulation discovery. Some of the most promising approaches were applied for efficient therapies of various diseases.
Keywords: Nitric oxide; cGMP; drug and formulation discovery; drug development; guanylyl cyclase; nitric oxide synthase; numerous efforts; phosphodiesterase; promising approaches; traditional Chinese medicine
Document Type: Research Article
Publication date: August 1, 2011
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