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Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.

Publisher: Bentham Science Publishers

Volume 18, Number 18, June 2011

Articles

Present and Future of PI3K Pathway Inhibition in Cancer: Perspectives and Limitations
pp. 2674-2685(12)
Authors: Ciraolo, E.; Morello, F.; Hirsch, E.

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Open Access Progress in the Preclinical Discovery and Clinical Development of Class I and Dual Class I/IV Phosphoinositide 3-Kinase (PI3K) Inhibitors
pp. 2686-2714(29)
Authors: J. Shuttleworth, S.; A. Silva, F.; R.L. Cecil, A.; D. Tomassi, C.; J. Hill, T.; I. Raynaud, F.; A. Clarke, P.; Workman, P.

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Targeting the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin Signaling Network in Cancer Stem Cells
pp. 2715-2726(12)
Authors: M. Martelli, A.; Evangelisti, C.; Y. Follo, M.; Ramazzotti, G.; Fini, M.; Giardino, R.; Manzoli, L.; A. McCubrey, J.; Cocco, L.

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mTOR Inhibitors: Facing New Challenges Ahead
pp. 2743-2762(20)
Authors: Mavrommati, I.; Maffucci, T.

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Targeting PDK1 in Cancer
pp. 2763-2769(7)
Authors: Raimondi, C.; Falasca, M.

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Serotonin Receptors of Type 6 (5-HT6): What can we Expect from them?
pp. 2783-2790(8)
Authors: Marazziti, D.; Baroni, S.; Catena Dell'Osso, M.; Bordi, F.; Borsini, F.

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Adenosine in the Inflamed Gut: A Janus Faced Compound
pp. 2791-2815(25)
Authors: B. Estrela, A.; Abraham, W.-R.

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Molecular Chaperone Hsp90 as a Target for Oxidant-Based Anticancer Therapies
pp. 2816-2825(10)
Authors: Beck, R.; Dejeans, N.; Glorieux, C.; C. Pedrosa, R.; Vasquez, D.; A. Valderrama, J.; B. Calderon, P.; Verrax, J.

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