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Virtual Screening Against Obesity

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Abstract:

The development of novel drugs against obesity is one of the top priorities of worldwide drug research. In recent years, it has been facilitated by the application of virtual screening methods. In this review, we give a short introduction into obesity-related protein targets and computer-aided drug design techniques. Furthermore, we highlight the most successful virtual screening studies, outline their results, and provide suggestions for future anti-obesity drug development.





Keywords: Anti-obesity drug; computer-aided drug design; ligand-based; molecular mechanisms; obesity; obesity targets; screening studies; structure-based; virtual screening

Document Type: Research Article

DOI: http://dx.doi.org/10.2174/092986711795656162

Publication date: May 1, 2011

More about this publication?
  • Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.
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