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Cancer-Targeting Multifunctionalized Gold Nanoparticles in Imaging and Therapy

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Abstract:

Nanotechnology has provided many promising nanoplatforms for targeted cancer imaging and therapy. Among these platforms, gold nanoparticles (GNPs) play a unique role in medicine because of their excellent physical and chemical properties. To expand the applications of GNPs in medicine, amounts of targeting moieties, imaging labels, and therapeutic agents have been integrated into these particles to form multifunctionalized GNPs. In this review, we highlight recent advances of the fabrication of cancer-targeting multifunctionalized GNPs and their applications in imaging and therapy.





Keywords: Gold nanoparticles; Nanotechnology; cancer imaging; cancer therapy; cancer-targeting; conjugation methods; multifunctionalized; targeting moieties; therapeutic payloads

Document Type: Research Article

DOI: https://doi.org/10.2174/092986711795656199

Publication date: 2011-05-01

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  • Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.
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