Voltage-Gated Sodium Channels: Mutations, Channelopathies and Targets
Keywords: Atrial Fibrillation; CHANNELOPATHIES; Coding exons; Drosophila; Epilepsy Associated; Infant; Neuropathic Pain; Scorpion Toxins; Sick Sinus Syndrome; Toxins; Voltage-gated sodium channel; antiepileptic drugs; aromatic tyrosine; arrhythmic syndromes; atrial fibrillation; atrial standstill; cardiac cells [41-4; cardiac death; celectrocardiogram; cell adhesion; channel trafficking; channel-selective blocker; channelopathy; chromosome; complex multimeric structure; density; depolarization; febrile seizure; fibrillation; ganglion; gating modulation; glutamic acid; heterologous expression system; hreshold channel; hyperpolarization-activated; hypoexcitability; hypokalemic periodic paralysis; insecticide pyrethroids; ion selectivity; mammalian isoforms; microglial cells; micromolar; modifying -subunits; myotonia; myotonia fluctuans; neonatal-infantile seizure; pacemaker; pain; paralysis; paramyotonia congenita; phenylalanine; phosphorylation; polar; potassium-aggravated myotonia; scorpion venom; sinoatrial; sinus node dysfunction; skeletal muscle; sodium channel mutations; sodium channel subtypes; stability of the membrane; subtype selective sodium channel blockers; subtype selective sodium channel toxins; tachyarrhythmia; tachycardia-bradycardia syndrome; trigeminal ganglia; two hydrophobic; ventricular myocar-dium; ventricular tachycardia
Document Type: Research Article
Publication date: 2011-01-01
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