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Authors: Sink, R.; Gobec, S.; Pecar, S.; Zega, A.
Source: Current Medicinal Chemistry, Volume 17, Number 34, December 2010, pp. 4231-4255(25)
Publisher: Bentham Science Publishers
Keywords: 2-amino-3-carbonyl tiophenes; 2-hydroxyphenylhydrazones; ALARM NMR; Acylhydrazides; Azoalkanals; CAC; CHAPS; CLND; Chymotrypsin; Clioquinol; Delavirdine; Enzyme Concentration; Epoxides; Glyburide; HTS; Hydroxyphenilhydrazones; Incubation Effect; Light Scattering; NMR; Nitroalkanes; Oxaprozin; PAINS; Perhaloketones; Plasmon Resonance; SRR (structure-reactivity relationship); Shoichet; Sulfonates; Thioepoxides; WaterLOGSY spectrum; aggregate-based promiscuous inhibitors; allopurinol; angiogenin; b-lactamase; baseline enzyme; chicken DHFR; cysteine proteases; dihydrofolate; drug discovery; hydrogen-deuterium; indiscriminate; mechanism of false-positive inhibition; metalloproteinase; methods for detecting false positives; microsecond; misinformed; more sophisticated; nicardipine; nonleadlike; omeprazole; optical biosensor surface; perplexing; photoactive dyes; prioritization; promiscuous inhibitors; pronounced capillarity; reactive compounds; red-horseradish; stoichiometry; sulfhydryl group; tetraiodophenolphthalein; thiol-reactive
Document Type: Research Article
Publication date: December 1, 2010