Effects of the Novel Non-Peptidyl Low Molecular Weight Radical Scavenger IAC in Different Models of Inflammation: A New Perspective in Anti-Inflammatory Therapy
Keywords: Alzheimer's disease; FREE RADICALS; IAC; Inflammation; Inflammatory bowel dis-eases (IBD); L-arginine; L-citrulline; Lipid Peroxidation; Neuroprotection; Neuroprotective Properties; PGE2; Parkinson's disease; RNS; ROS; Radical Scavenger; bilateral common carotid artery occlusion (BCCO); bis (1-hydroxy-2,2,6,6-tetramethyl-4-piperidinyl)-decandioate; c-Jun N-terminal kinase (JNK); cyclooxygenase; deoxyribo-nucleic acid (DNA); dysregulated; electron paramagnetic reso-nance (EPR); excitotoxicity; gastric ulcers; gastrointesti-nal (GI); guanosine diphosphate (GDP); guanosine triphosphate (GTP); hydrophylic-ity/lipophylicity; indomethacin; intrinsic property; kappa B kinase (IKK-b); leukocyte; maladaptive re-sponse; metalloproteinase; mitogen-activated protein kinase (p38-MAPK); monocyte chemo-attractant protein-1 (MCP-1); myeloperoxidase; neurodegenerative diseases; neurological disorders; nitric oxide (NO); nitric oxide synthase; nitrogen species; nitrosative stress; non steroidal anti-inflammatory drugs (NSAIDs); oxidative stress status; pancreatic islets; peroxyl; superoxide; peroxynitrite radicals; prostaglandins (PGs); protein kinase C (PKC); re-active oxygen; reactive oxygen species (ROS); sclerosis; superoxide dismutase; vascular cell adhesion molecule-1 (VCAM-1); xanthine oxidase
Document Type: Research Article
Publication date: 2010-11-01
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