Emerging Roles for Riboflavin in Functional Rescue of Mitochondrial β-Oxidation Flavoenzymes
Keywords: Disease; Flavin; Mitochondrial metabolism; Protein folding; Riboflavin; Riboflavin-responsive; acyl-CoA dehydrogenase defi-ciency (RR-MADD); acyl-carnitine translocase (CAT); aminomonophosphate (AMP); biophysics; carbonylation; carnitine palmitoyl transferase I (CPT I); cell damage; conformational destabilisation; dehydrogenases; electron transferring flavoprotein (ETF); ethylmalonic-adipic aciduria; fatty acid -oxidation pathway; fatty acid oxidation (FAO); flavin adenine dinucleotide (FAD); flavin mononucleotide (FMN); flavoenzymes; glutaryl-CoA dehydrogenase; heme biosynthesis; isoalloxazine ring system; isovaleryl-CoA dehydrogenase (IVD); lymphoid cells; mass spec-trometry; oxidative folding; respiratory complexes; riboflavin transporter 2 (RFT2); semiquinone form; semiquinone radical; short chain acyl-CoA dehydrogenase (SCAD); vitamin B2
Document Type: Research Article
Publication date: 2010-11-01
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