Tailoring NO Donors Metallopharmaceuticals: Ruthenium Nitrosyl Ammines and Aliphatic Tetraazamacrocycles
Keywords: = quantum yield of release of NO; Antiparasitic Effects; Bioavailability; Biodistribution; HepG2 cells; Hipotensive Properties; Mouse Hippocampus; N-hydroxyguanidines; NRU = neutral red uptake; P(OEt)3 = triethylphosphite; PAMAM = polyamidoamine dendrimers; RCR = respiratory control ratio; Ruthenium; T. cruzi = Trypanosoma cruzi; TI = therapeutic; Toxicity; ali-phatic tetraazamacrocyles; aliphatic tetraazamacrocyles; biological applications; differential pulse polarography (DPP); iron-cluster-containing; mac = macrocyclic ligand; mitochondrial permeability transition (MPT); neurotransmission; nic = nicotinamide; nitric oxide carriers; nitric oxide synthase enzyme (NOS); nitrosyls; pathogens killing; performing redox reactions; photodynamic therapy (PDT); pseudo-octahedral complexes; ruthenium nitrosyl ammines; trypanosomatids
Document Type: Research Article
Publication date: 2010-11-01
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