Contributions of Computational Chemistry and Biophysical Techniques to Fragment-Based Drug Discovery
Keywords: Computational chemistry; X-ray crystallography; fluorescence-based thermal shift assay; fragment-based screening; isothermal titration calorimetry; mass spectrometry; nuclear magnetic resonance spectroscopy; surface plasmon resonance
Document Type: Research Article
Affiliations: Structural Biology Laboratory,Centro de Investigacion Principe Felipe, Avda. Autopista del Saler 16, E-46012 Valencia, Spain.
Publication date: 2010-06-01
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