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New and Bioactive Natural Products Isolated from Madagascar Plants and Marine Organisms

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Madagascar, the world's fourth biggest island has a unique biodiversity. The interest on the phytochemical investigation of Malagasy plant and marine natural products started from the isolation of the potent anti-cancerous bisindole alkaloids: vinblastine and vincristine. In this paper, work published in the last two decades (1991-2009) on 262 new natural products isolated from Malagasy higher plants, liverworts and marine organisms is reviewed. Several results on the bioassays of the isolated new natural products have been reported.

Keywords: Madagascar; bioactivities; biodiversity; marine organisms; natural products; plants

Document Type: Research Article


Affiliations: Department of Chemistry, M/C 0212, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061-0212, USA.

Publication date: 2010-04-01

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