Natriuretic Peptides in Septic Patients
Sepsis is a complex condition that can lead to multiorgan failure, shock and death. The number of people developing sepsis is still increasing (approximately 750,000 cases of sepsis occur annually in the USA).
Both ANP and pro-ANP have attracted interest as new markers for sepsis. Reports indicate that ANP or BNP levels are elevated in septic patients. However, many mechanisms are still unexplained. This situation is complicated by the fact that contradictory results have been published. There are several reasons for this controversy including differences in the techniques used to assay natriuretic peptides. Nevertheless, natriuretic peptides might eventually prove useful for the diagnosis and/or the treatment of septic patients.
Document Type: Research Article
Affiliations: Department of Anaesthesiology and Intensive Care Unit, Military Medical Academy University Hospital in Lodz, Medical University of Lodz, Hallera Sq 1; 90-647 Lodz, Poland.
Publication date: 01 October 2009
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