Naturally Occurring Xanthones; Latest Investigations: Isolation, Structure Elucidation and Chemosystematic Significance

Authors: El-Seedi, Hesham R.; El-Ghorab, Dina M.H.; El-Barbary, Mai A.; Zayed, Mervat F.; Goransson, Ulf; Larsson, Sonny; Verpoorte, Rob

Source: Current Medicinal Chemistry, Volume 16, Number 20, July 2009 , pp. 2581-2626(46)

Publisher: Bentham Science Publishers

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Abstract:

In this review, an updated literature survey covering the reports of naturally occurring xanthones in the period of 2005-2008 is presented. In some 143 studies, the isolation of 264 different xanthones from 36 plant species (representing 15 genera in 6 families of higher plants), 7 species of fungi, and 1 lichen species were reported. Of these, 122 compounds were isolated for the first time from nature. We discuss plant origin, the way of separation, and spectral analysis done for structure elucidation, along with a brief discussion of the chemosystematic significance.

Keywords: Chemosystematics; natural xanthones; higher plants; fungi; separation; structure elucidation

Document Type: Research article

DOI: http://dx.doi.org/10.2174/092986709788682056

Affiliations: 1: Pharmacognosy Division, Department of Medicinal Chemistry, Uppsala University, Box 574, SE-75123 Uppsala, Sweden.

Publication date: 2009-07-01

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Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.