miRNAs in the Biology of Cancers and Viral Infections
Authors: Yeung, Man Lung; Bennasser, Yamina; Jeang, Kuan-Teh
Source: Current Medicinal Chemistry, Volume 14, Number 2, January 2007 , pp. 191-197(7)
Publisher: Bentham Science Publishers
Abstract:MicroRNAs (miRNAs) are non-coding small RNAs that play important roles in a variety of biological pathways including cellular proliferation and apoptosis. Recent studies have linked the expression of selected miRNAs to carcinogenesis and viral pathogenesis. Here, we will discuss examples of roles served by cellular miRNAs and virus-encoded miRNAs in the development of cancers and viral diseases.
Document Type: Research Article
Affiliations: Building 4, Room 306, 9000 Rockville Pike, Bethesda, MD 20892-0460, USA.
Publication date: 2007-01-01
- Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.