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Determination of Bioactive Constituents in Traditional Chinese Medicines by CE with Electrochemical Detection

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Abstract:

This paper reviews the recent advances and the key strategies in capillary electrophoresis (CE) with electrochemical detection (ECD) for separating and detecting a variety of bioactive constituents in traditional Chinese medicines (TCMs). The subjects covered include the separation modes for the CE analysis of the constituents in TCMs, the CE-ECD system, the sample preparations of TCMs, the ECD of TCMs, the applications of CE-ECD in the determination of various bioactive constituents in Chinese medicinal materials and their preparations, the identification and differentiation of TCMs by CE-ECD, and future prospects. It is expected that CE-ECD will become a powerful tool in the herbal medicinal fields and will lead to the creation of truly routine devices for TCM analysis..

Keywords: Traditional Chinese medicine; amperometry; bioactive constituent; capillary electrophoresis; differentiation; electrochemical detection; electrode; pharmaceutical analysis

Document Type: Research Article

DOI: https://doi.org/10.2174/092986706778201657

Affiliations: Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China.

Publication date: 2006-09-01

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  • Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.
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