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Chemical Toxicity on HeLa Cells

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Abstract:

HeLa cells were named for Henrietta Lacks, who died in 1952 from an infection of a special type of cancer. Margaret Gey, her physician, started working with these cancer cells that are still used for medical research. In the present review, an attempt has been made to collect the data for the effects of different chemicals on HeLa cells and to discuss them by the formulation of a total number of 22 QSAR.

Keywords: Hammett parameters; QSAR; Verloop's sterimol; hydrophobicity; molar refractivity; molar volume

Document Type: Research Article

DOI: http://dx.doi.org/10.2174/092986706775527910

Affiliations: Department of Chemistry, Pomona College, Claremont, CA 91711 USA.

Publication date: February 1, 2006

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  • Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.
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