Voglibose (Basen®, AO-128), One of the Most Important α-Glucosidase Inhibitors
Authors: Chen, Xiaolong; Zheng, Yuguo; Shen, Yinchu
Source: Current Medicinal Chemistry, Volume 13, Number 1, January 2006 , pp. 109-116(8)
Publisher: Bentham Science Publishers
Abstract:The number of people with diabetes is expected to rise from the current estimated 150 million to 220 million in 2010 and 300 million in 2025, and 90% is Type 2 diabetes or non-insulin dependant diabetes mellitus (NIDDM). Voglibose, one of the most important α-glucosidase inhibitors, delays the digestion and absorption of carbohydrates, thereby inhibiting postprandial hyperglycemia and hyperinsulinemia, and is the aid in the treatment of diabetes. In this paper, properties and the preparation of voglibose are reviewed.
Document Type: Research Article
Affiliations: Institute of Bioengineering, Zhejiang University of Technology, Hangzhou 310032, PR China;
Publication date: 2006-01-01
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