Xanthones-A Structural Perspective

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Abstract:

Xanthones, synthesized or isolated from a natural source, display a wide range of biological and pharmacological activities. In a few cases, their chemical characterization has involved the structure elucidation by single crystal X-ray diffraction. The purpose of this review is to assess in detail this three-dimensional structural data, and thus contribute to a better understanding of the molecular mechanisms involved in the different biological activities presented by xanthones.

Keywords: crystallography; three-dimensional structure; xanthone

Document Type: Review Article

DOI: http://dx.doi.org/10.2174/092986705774370727

Affiliations: Instituto de Biologia Molecular e Celular, Rua do Campo Alegre, 823, 4150 Porto, Portugal.

Publication date: October 1, 2005

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  • Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.
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