Quinoxaline 1,4-Dioxide: A Versatile Scaffold Endowed With Manifold Activities
In this review article we report the biological properties, the mode of action and Structure Activity Relationship (SAR) studies of the QdNO derivatives. Furthermore, some cytogenetic and genotoxic effects, classical and more recent method of synthesis, the quinoxaline 1,4-dioxides, and some of their most important reactions, were also reported.
Keywords: animal growth promoting; antibacterial activity; anticandida activity; antimycobacterial activity; antiprotozoal activity; dioxides; hypoxia-selective activity; mutagenicity; quinoxaline; sar studies
Document Type: Review Article
Affiliations: Antonio Carta, Dipartimento Farmaco Chimico Tossicologico, Facolta di Farmacia, Universita di Sassari, via Muroni 23/a, 07100 Sassari, Italy.
Publication date: 2005-09-01
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