Positron-Emitting Isotopes Produced on Biomedical Cyclotrons

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Abstract:

This review will discuss the production and applications of positron-emitting radionuclides for use in Positron Emission Tomography (PET), with emphasis on radionuclides that can be produced onsite with a biomedical cyclotron. In PET the traditional radionuclides of choice are 11C, 13N, 15O and 18F and although they will be briefly discussed in this article, the emphasis of this review will be on 'non-standard' PET radionuclides that are generating increased interest by the medical research community.

Keywords: micropet; positron emission tomography; production methods; radioisotopes; radionuclides

Document Type: Review Article

DOI: http://dx.doi.org/10.2174/0929867053507397

Affiliations: Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S. Kingshighway Boulevard, Campus Box 8225, Saint Louis, MO 63110; USA.

Publication date: April 1, 2005

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  • Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.
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