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Monoamine Oxidases: Certainties and Uncertainties

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Abstract:

A great deal has been learned about the behaviour of monoamine oxidase in the 75 years since it was first discovered, but there is still a great deal left to understand. This review concentrates on the dynamic aspects of our knowledge of the interactions of MAO with substrates and inhibitors and how it may collaborate with other enzymes, with particular emphasis on aspects that remain to be clarified.

Keywords: inhibitors; monoamine oxidases; substrates

Document Type: Review Article

DOI: https://doi.org/10.2174/0929867043364810

Affiliations: Department of Biochemistry, Trinity College, Dublin 2, Ireland

Publication date: 2004-08-01

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  • Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.
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