Therapeutic Constituents and Actions of Rubus Species

Authors: Patel A.V.; Rojas-Vera J.; Dacke C.G.

Source: Current Medicinal Chemistry, Volume 11, Number 11, June 2004 , pp. 1501-1512(12)

Publisher: Bentham Science Publishers

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Abstract:

Rubus species (family Rosaceae) have been cultivated for centuries for their fruits. These and other parts of the plants have been used traditionally for therapeutic purposes. This article highlights these and the potential they can offer. The constituents reported in the various species and those demonstrated to exhibit pharmacological properties have been reviewed. In the search for biologically active compounds, one of the most frequently documented species of the genus is the raspberry plant R. idaeus, the leaves of which have been used traditionally as a uterine relaxant and stimulant during confinement, for the treatment of diarrhoea and similar enteric disorders and as an astringent. Investigations of other Rubus species have been conducted in the last twenty-five years, and have shown possible application for a wide range of indications, including bacterial infections, anxiety, pain and inflammation.

Keywords: rubus species; rosaceae; raspberry; traditional uses; chemical constituents; smooth muscle relaxant

Document Type: Review article

DOI: http://dx.doi.org/10.2174/0929867043365143

Affiliations: 1: School of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth, PO1 2DT, UK

Publication date: 2004-06-01

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Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.