Cytotoxic Natural Products from Formosan Plants and Marine Organisms

Authors: Lee S-S.; Chang W-L.

Source: Current Medicinal Chemistry, Volume 11, Number 11, June 2004 , pp. 1461-1477(17)

Publisher: Bentham Science Publishers

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Abstract:

Cytotoxic natural products isolated from Formosan plants and marine organisms till December, 2002, by local scientists or Taiwanese researchers have been reviewed. A total of about 200 compounds belonging to six types of chemical structures are listed or / and described in this article. Several compounds with special or selective activity have been described in more details. Some structure-activity relationships for the compounds of the same skeleton are drawn to clarify the possible pharmacophores.

Keywords: cytotoxicity; formosan plants; marine organisms; in vitro assay; structural properties

Document Type: Review article

DOI: http://dx.doi.org/10.2174/0929867043365125

Affiliations: 1: School of Pharmacy, College of Medicine, National Taiwan University, 1 Jen-Ai Rd., Sec. 1, Taipei 100, Taiwan, China

Publication date: 2004-06-01

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Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.