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Intravenous and Regional Paclitaxel Formulations

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Paclitaxel has been proven to be effective against different types of cancer. A delivery system loaded with paclitaxel at tumor site should provide a high local concentration of the drug detrimental to malignant cells, which prevents the re-growth and metastasis of tumor. In this review, paclitaxel formulations for systemic and for intratumoral administration are discussed.
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Keywords: delivery systems; formulations; intratumoral delivery; paclitaxel; polymers

Document Type: Review Article

Affiliations: Department of Medicinal Chemistry and Natural Products, The Hebrew University, School of Pharmacy-Faculty of Medicine, Jerusalem 91120, Israel.

Publication date: 2004-02-01

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  • Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.
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