Predicting Molecular Interactions in silico: II. Protein-Protein and Protein- Drug Docking
Abstract:This article reviews the docking field starting from basic docking algorithms and describing the latest advances. We present the algorithmic framework and classify the state of-the-art methods. We point out the bottlenecks of the methods, like flexibility, absence of absolute scoring functions and explain what types of information can potentially be added to improve the results.
Document Type: Review Article
Affiliations: School of Computer Science, Tel Aviv University, Tel Aviv 69978, Israel.
Publication date: January 1, 2004
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