Neurotransmission and Neurotoxicity by Nitric Oxide, Catecholamines, and Glutamate: Unifying Themes of Reactive Oxygen Species and Electron Transfer
Abstract:This review treats the mechanism of nitric oxide, catecholamines, and glutamate as important neurotransmitters and as neurotoxins, based on involvement of reactive oxygen species (ROS) and electron transfer (ET). ROS and ET can serve as a unifying framework for both transmission and toxicity, with ROS concentration being a crucial issue. Cell signaling, electrochemistry, antioxidants, and apoptosis are also discussed.
Document Type: Review Article
Affiliations: Department of Chemistry, San Diego State University, San Diego, California 92182-1030, USA.
Publication date: December 1, 2003
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