Novel Hydroxamate and Anilide Derivatives as Potent Histone Deacetylase Inhibitors: Synthesis and Antiproliferative Evaluation
Keywords: anilide derivatives; anticancer agents; hdac enzymes; hdacs; histone deacetylase inhibitors; hydroxamate; structure-activity relationships; suberoylanilide hydroxamic acid; trichostatin a; tsa
Document Type: Review Article
Affiliations: Department of Medicinal Chemistry, MethylGene Inc., 7220 Frederick-Banting, Montreal, Quebec H4S 2A1, Canada.
Publication date: 2003-11-01
- Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.