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An Over Four Millennium Story Behind Qinghaosu (Artemisinin)-A Fantastic Antimalarial Drug from a Traditional Chinese Herb

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Abstract:

This article reviews the discovery and the further studies on qinghaosu and its derivatives or analogs over the last decades in the fields of medicinal chemistry and some pharmacology research, with an emphasis on the progress achieved in China.

Keywords: antimalarial; artemisinin; chemistry; mechanism of action; pharmacology; structure determination; synthesis

Document Type: Review Article

DOI: https://doi.org/10.2174/0929867033456710

Affiliations: State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 FengLin Road, Shanghai 200032, China.

Publication date: 2003-11-01

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  • Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.
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