Chemistry and Biology of New Marine Alkaloids from the Indole and Annelated Indole Series

Authors: Aygun A.; Pindur U.

Source: Current Medicinal Chemistry, Volume 10, Number 13, July 2003 , pp. 1113-1127(15)

Publisher: Bentham Science Publishers

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Abstract:

Chemistry and biology of marine natural products from the indole and annelated indole series have become an attractive research field for development of new pharmacological lead substances. In the past years some of the isolated natural organic compounds were synthesized by chemists and evaluated with great enthusiasm to find new lead natural compounds against different diseases. In this review the latest results for new compounds including isolation, biological evaluation, synthetic pathways and some retrosynthetic analyses are summarized.

Keywords: marine alkaloids; annelated indole series; marine natural products

Document Type: Review article

DOI: http://dx.doi.org/10.2174/0929867033457511

Publication date: 2003-07-01

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Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.