Skip to main content

Synergy in Plant Medicines

Buy Article:

$63.00 plus tax (Refund Policy)


The notion that medicines derived from plants depend for their action on active principles present has to be modified in view of the findings that there are, in many cases, adjuvant substances in the plant which enhance the activity of the components actually responsible for the effect. This synergy may involve protection of an active substance from degradation by enzymes, it may facilitate transport across barriers such as cell and organelle walls, it may overcome multi-drug resistance mechanisms or provide other signals to the host's cells that result in higher efficacy of the crude drug when compared with isolated components. The many plant substances that stimulate the immune system, often at very low doses, have not been reviewed as this is not strictly speaking synergy. Some of the evidence for the phenomena described is reviewed and its bearing on phytotherapy commented.

Keywords: Plant Medicines; multi-drug resistance; phytotherapy

Document Type: Review Article


Publication date: January 1, 2003

More about this publication?
  • Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more